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OED for dose inhomogeneity

Schneider et al, 2005

• Any dose distribution in an organ is equivalent and

corresponds to the same OED if it causes the same

radiation-induced cancer incidence.

• For low doses, the OED is simply the average organ dose,

because the dose–response relationship for cancer

induction is in these cases a linear function of the dose

with good precision.

• However, for high doses, it is different from the average

dose, because the cell sterilization effects at high doses

must also be considered.