OED for dose inhomogeneity
Schneider et al, 2005
• Any dose distribution in an organ is equivalent and
corresponds to the same OED if it causes the same
radiation-induced cancer incidence.
• For low doses, the OED is simply the average organ dose,
because the dose–response relationship for cancer
induction is in these cases a linear function of the dose
with good precision.
• However, for high doses, it is different from the average
dose, because the cell sterilization effects at high doses
must also be considered.