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Most organs have several radiation complications.
Lung: radiation pneumonitis, fibrosis, functional measures
Brainstem: necrosis, neuropathy, radiological changes
Complications may have different degrees of severity; as an example lung
toxicity can be graded from 1 cough to 5 death.
The dosimetric predictors and NTCP parameter sets can vary according to
the grade of toxicity which the clinical data refer to.
Clinical data (1)
Ideal system:
complete
to record any score
reproducible
inter/intra-observer variability low
sensitive
able to detect changes in treatment intensity