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Changes in anatomy over the course of treatment

•

10 H&N pts, IMRT

•

CTVs and OARs delineated on CBCT at the10

th

, 15

th

, 20

th

,

25

th

treatment session and then compared with the planning

CT

•

A statistically significant increase of larynx volume at the 20

th

and 25

th

CBCT was observed

•

The main benefit of replanning could be to preserve parotis,

not to reevaluate the target

•

Check point at the 3

rd

week of radiotherapy in this pts

cohort

(Cozzolino

et al

, 2014)