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Primary and Secondary Evaluation of Method SJW-14
SJW-14:
Chemical Composition of
Hypericumrumeliacum
BIOSS. Essential Oil.A new Chemotype
of This pharmologicallyvaluble species?
Author(s):
Chemistry & Biodiversity – Vol. 9 (2012), Niko S. Radulovic´* and Polina D. Blagojevic
S
UMMARY OF
M
ETHOD
:
G
ENERAL
C
OMMENTS
:
The method presented results dealing with the extraction of the essential oil of Hypericum rumeliacum
aerial parts and analysis of its constituents through GC and GC/MS techniques. The results were used
with MVA to determine if there are chemo type differences that exist within H. rumeliacum.
P
ROS
/S
TRENGTHS
:
This method used nitrogen to evaporate solvent which reduces loses of volatiles.
C
ONS
/W
EAKNESSES
:
This method pertains to only plant tissues and not supplements. It’s used for H. rumelaicum, not St.
Johns Wort (H. perforatum). This is not a quantitative method and is not applicable to the SMPR.
EXPERT REVIEW PANEL VOTE
AND
RECOMMENDATION
MOTION: Not to consider this method for First Action Official Method status.
Es-Safi, Mudge (Unanimous) Motion Passed
ERP PROFILE SUMMARIES
96