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Existing Methods (General)
•
Synthetic: S/R = 50/50
•
Natural: 2-4 Months to S/R = 50/50
•
S and R are Convertible
HPLC Method for Potency and Purity Test
Some Factors about Racemization to Consider:
Existing Methods (General)
A Sample Chromatogram of SAMe Degradation Products
0
2
4
6
8
10
12
min
350
mAU
300
250
200
150
100
50
0
Adenosine
PTSA
SAH
SAM
DMTA
400