171 / 266
144
W
E
D
N
E
S
D
A
Y
2701-Pos
Board B78
STRUCTURAL AND BIOCHEMICAL INVESTIGATIONS ON THE CATALYTIC
MECHANISM OF PYRIDOXAL KINASE (PDXK) FROM SALMONELLA
TYPHIMURIUM AND ITS INTERACTIONS WITH PLP-DEPENDENT EN-
ZYMES.
G. Deka
, J. F. Benazir, J. N. Kalyani, H. S. Savithri, M.R.N. Murthy
2702-Pos
Board B79
MOLECULAR BASIS FOR COHESIN ACETYLATION BY ESTABLISHMENT OF
SISTER CHROMATID COHESION N-ACETYLTRANSFERASE (ESCO1).
Yadil-
ette Rivera-Colon
, AndrewMaguire, Glen P. Liszczak, Ronen Marmorstein
2703-Pos
Board B80
ORIGINS OF CATALYTIC SPECIFICITY IN BACTERIAL OLIGOSACCHARYL-
TRANSFERASE.
Brittany R. Morgan
, Francesca Massi
2704-Pos
Board B81
MOLECULAR MECHANISM OF THE CATALYTIC REACTION OF NO REDUC-
TASE REVEALED BY NOVEL TIME-RESOLVED VISIBLE/IR ABSORPTION
SPECTROMETERS WITH MICROFLUIDIC DEVICE.
Tetsunari Kimura
, Hanae
Takeda, Shoko Ishii, Takehiko Tosha, Yoshitsugu Shiro, Minoru Kubo
2705-Pos
Board B82
DROPLET-BASED MICROFLUIDICS FOR MEASURING ENZYMATIC AC-
TIVITIES: APPLICATION TO L-ASPARAGINASE USED IN ANTILEUKEMIC
THERAPY.
Manfred W. Konrad
, Christos S. Karamitros, Joanan Lopez
Morales, Jean-Christophe Baret
2706-Pos
Board B83
EDUCATION TRAVEL AWARDEE
TRANSGLUTAMINASE FACTOR XIII CROSS-LINKS REACTIVE GLUTAMINES
IN DISORDERED REGIONS OF FIBRINOGEN αC.
Kelly Njine Mouapi
, Kerrie
A. Smith, Robert A.S Ariens, Helen Philippou, Muriel C. Maurer
2707-Pos
Board B84
CHARACTERIZATION OF THE PYRUVATE OXIDASE CIDC FROM S. AURE-
US.
Xinyan Zhang
, Kenneth Bayles, Sorin Luca
2708-Pos
Board B85
PHOSPHODIESTERASE 5 SIGNALS THROUGH HIPPO/TAZ PATHWAY IN
MAINTAINING STEMNESS OF PROSTATE CANCER CELLS.
Naihua Liu
,
Xing Ji, Ximei Wu
2709-Pos
Board B86
THE NEET PROTEINS MEDIATE IRON-SULFUR CLUSTER TRANSPORT FROM
THE MITOCHONDRIA TO CYTOSOLIC PROTEINS.
Colin H. Lipper
, Mark L.
Paddock, Rachel Nechushtai, Patricia A. Jennings
2710-Pos
Board B87
KINETIC AND STRUCTURAL ANALYSES OF A DYNAMIN MECHANOEN-
ZYME.
Blake Hill
, Nolan Kennedy
2711-Pos
Board B88
KINETIC DISSECTION OF THE PRE-EXISTING CONFORMATIONAL EQUILIB-
RIUM IN THE TRYPSIN FOLD. Austin D. Vogt,
Pradipta Chakraborty
, Enrico
Di Cera
2712-Pos
Board B89
INFLUENCE OF DIFFUSION ON THE KINETICS OF MULTISITE PHOSPHORY-
LATION.
Irina V. Gopich
, Attila Szabo
2713-Pos
Board B90
EFFECTS OF METAL SUBSTITUTION IN HDAC8 AND IMPLICATIONS FOR
KINETICS.
Nathan Gallup
, Michael Nechay
2714-Pos
Board B91
SYNTHESIZING CAGED-NAD MOLECULES TO CONDUCT LAUE TIME-
RESOLVED CRYSTALLOGRAPHY MEASUREMENTS ON HMGCOA REDUC-
TASE.
Vatsal Purohit
, Farbod Salahi, Nic Steussy, Paul Helquist, Olaf Weist,
Cynthia Stauffacher
2715-Pos
Board B92
DISTRIBUTION OF IMMOBILIZED ENZYMES ON THE SURFACE AND INTO
THE MESOPOROUS SILICA PARTICLE.
Pegah S. Nabavi Zadeh
, Björn
Åkerman
Intrinsically Disordered Proteins (IDP) and
Aggregates: Aß, Tau, and
α
-Synuclein
(Boards B93 - B113)
2716-Pos
Board B93
WHY PRESSURE IS BAD FOR YOUR BRAIN? HYDROSTATIC PRESSURE
PROMOTES AGGREGATION OF ALPHA-SYNUCLEIN IN CELLS.
Urszula P.
Golebiewska
, Suzanne Scarlata
2717-Pos
Board B94
AGGREGATION AND FIBRILLATION OF α-SYNUCLEIN BY POLYMORPH
PATCHY PARTICLES.
Ioana M. Ilie
, Wouter K. den Otter, Wim J. Briels
2718-Pos
Board B95
ALPHA-SYNUCLEIN AND ITS INTERACTION WITH CYTOSKELETON (ASSOCI-
ATED) PROTEINS: IMPLICATIONS IN PARKINSON’S DISEASE.
Senthil Kumar
Thangaraj
, Lisanne Dijk, Mireille Claessens
2719-Pos
Board B96
MOLECULAR DYNAMICS SIMULATIONS OF ALPHA-SYNUCLEIN ENSEMBLE
FRET MEASUREMENTS FROM DIFFERENT FORCE FIELDS. Reinhard
Klement,
Timo Graen
, Asaf Grupi, Elisha Haas, Helmut Grubmüller
2720-Pos
Board B97
UNCONVENTIONAL CHAPERONE INHIBITS AMYLOID FORMATION BY
PROMOTING OFF-PATHWAY AGGREGATION. Illes-Toth Eva, Shah Maliha,
Wu Nelson, Verzini Silvia, Selenko Philipp, Wanker E. Erich,
Jan Bieschke
2721-Pos
Board B98
EDUCATION TRAVEL AWARDEE
MULTI-TRGET THERAPEUTIC POTENTIAL OF GREEN TEA CATECHINS AND
BLACK TEA THEAFLAVINS TOWARD Aβ-INDUCED SIGNAL PATHWAYS
INVOLVED IN ALZHEIMER’S DISEASE.
Shelby E. Chastain
, Melissa Moss
2722-Pos
Board B99
EFFECT OF ACIDIC PH ON THE STABILITY OF ALPHA-SYNUCLEIN DI-
MERS.
Zhengjian Lv
, Alexey V. Krasnoslobodtsev, Yuliang Zhang, Daniel
Ysselstein, Jean-Christophe Rochet, Scott C. Blanchard, Yuri L. Lyubchenko
2723-Pos
Board B100
THE INTERPLAY OF INTRINSIC DISORDER AND MACROMOLECULAR
CROWDING ON α-SYNUCLEIN FIBRIL FORMATION.
Nobu C. Shirai
,
Macoto Kikuchi
2724-Pos
Board B101
ASSESSING N-TERMINAL MODIFICATIONS ON ALPHA-SYNUCLEIN STRUC-
TURE AND FUNCTION.
Siobhan Toal
, David DeWitt, Adam Trexler, Mark
Brown, Elizabeth Rhoades
2725-Pos
Board B102
EFFICIENT LIPID PEROXIDATION CATALYZED BY AMYLOID-BETA-COPPER
COMPLEX: OBSERVATION OF CHEMICAL OSCILLATION AND CHAOS.
Ciaran McFarlane, Paul Girvan, Thomas Branch,
Liming Ying
2726-Pos
Board B103
SELF-ASSEMBLY OF FULL-SIZE AMYLOID BETA 40 PROTEINS IN DI-
MERS.
Mohtadin Hashemi
, Yuliang Zhang, Zhengjian Lv, Yuri L. Lyub-
chenko
2727-Pos
Board B104
X-RAY DIGITAL AGGREGATED DYNAMICS OF INTRINSICALLY DISORDERED
PROTEINS.
Naruki Hara
, Yufuku Matsushita, Keigo Ikezaki, Hiroshi
Sekiguchi, Naoya Fukui, Yasushi Kawata, Yuji C. Sasaki