170 / 266
W
E
D
N
E
S
D
A
Y
143
2676-Pos
Board B53
STRUCTURAL BASIS OF MEMBRANE TARGETING BY THE INNATE IMMU-
NITY ADAPTOR TIRAP.
Xiaolin Zhao
, Shuyan Xiao, Jeffrey Ellena, Geoffrey
Armstrong, Daniel Capelluto
2677-Pos
Board B54
NOVEL MODULATORS OF GLYCINE RECEPTORS.
Marta M. Wells
, Andrew
Maxwell, Yan Xu, Pei Tang
2678-Pos
Board B55
SCREENING OF A PROTEIN-PROTEIN INTERACTION FOCUSED LIBRARY
TARGETING BIG3-PHB2 INTERACTION.
Takeru Chigira
, Satoru Nagatoishi,
Kouhei Tsumoto
2679-Pos
Board B56
PEPTIDES DERIVED FROM CXCL8 BASED ON IN SILICO ANALYSIS INHIBIT
CXCL8 INTERACTIONS WITH ITS RECEPTOR CXCR1. Chun-Chun Chang,
Shinn-Jong Jiang, Je-Wen Liou, Yi Chung,
Hao-Jen Hsu
2680-Pos
Board B57
PROTEIN-PEPTIDE DOCKING WITH HIGH CONFORMATIONAL FLEXIBILITY
USING CABS-DOCK WEB TOOL.
Maksim Kouza
, Maciej Blaszczyk, Mateusz
Kurcinski, Lukasz Wieteska, Aleksander Debinski, Andrzej Kolinski,
Sebastian Kmiecik
2681-Pos
Board B58
INCREASED FLEXIBILITY OF LOCAL CONFORMATION IN THE N-TERMINAL
DOMAIN OF MDMX ENHANCES LIGAND-BINDING AFFINITY.
Lingyun Qin
,
Rong Chen, Huili Liu, Zhengding Su
2682-Pos
Board B59
THE INFLUENCES OF DRUG-RESISTANT MUTATIONS OF EGFR TO THE
INHIBITOR BINDING AFFINITY AND THE DRUG TARGET SELECTIVITY PRO-
FILES.
Jiyong Park
, Joseph J. McDonald, Russell C. Petter, Ken Houk
2683-Pos
Board B60
THE IMPACT OF EXPERIMENTAL, PROTEIN STRUCTURE ON OUR ABILITY
TO MODEL PROTEIN FUNCTION.
Oleg Y. Borbulevych
, Lance M.
Westerhoff
2684-Pos
Board B61
HEPARIN-SCLEROSTIN INTERACTIONS FROM SURFACE PLASMON RESO-
NANCE AND MOLECULAR DYNAMICS SIMULATIONS.
J. Joel Janke
, Fuming
Zhang, Robert J. Linhardt, Angel E. Garcia
2685-Pos
Board B62
MOLECULAR BASES BASIS OF ANTIBIOTIC TRANSLOCATION ACROSS
OUTER MEMBRANE PORINS OF ENTEROBACTER AEROGENES.
Jiajun
Wang
, Muriel Masi, Harsha Bajaj, Mohamed Kreir, Mathias Winterhalter,
Niels Fertig
2686-Pos
Board B63
STUDY OF LIGAND BINDING SELECTIVITY OF HISTONE DEACETYLASES
BY REPLICA-EXCHANGE UMBRELLA SAMPLING MOLECULAR DYNAM-
ICS SIMULATIONS.
Shuichiro Tsukamoto
, Yoshitake Sakae, Yukihiro Itoh,
Takayoshi Suzuki, Yuko Okamoto
2687-Pos
Board B64
INTERNATIONAL TRAVEL AWARDEE
PREDICTING LIGAND SELECTIVITY ACROSS BROMODOMAIN FAMI-
LIES.
Matteo Aldeghi
, Alexander Heifetz, Michael J. Bodkin, Stefan Knapp,
Philip C. Biggin
2688-Pos
Board B65
A MOLECULAR DYNAMICS STUDY OF MICHAELIS COMPLEX FOR DESIGN-
ING SELECTIVE TRANSITION STATE ANALOG INHIBITORS FOR CYSTEINE
PROTEASE CALPAIN-2.
Payal Chatterjee
, Abdelaziz Alsamarah, David Kent,
Li Qian, David Wych, Christine N. Pham, Alla Avetisyan, Steven Standley,
Michel Baudry, Yun Luo
2689-Pos
Board B66
MECHANISM OF UREA CONDUCTION THROUGH H. PYLORI UREI.
Ugur
Akgun
2690-Pos
Board B67
CPOW TRAVEL AWARDEE
DISSECTING THE CONTRIBUTION OF KINASE CONFORMATIONAL REOR-
GANIZATION ENERGIES TO INHIBITOR SELECTIVITY.
Sonya M. Hanson
,
Lucelenie Rodriguez, Julie M. Behr, Andrea Rizzi, Daniel L. Parton, Kyle A.
Beauchamp, Joshua H. Fass, Jan-Hendrik Prinz, Sarah E. Boyce, Markus A.
Seeliger, Nicholas M. Levinson, John D. Chodera
2691-Pos
Board B68
MULTISCALE MODELING OF DENDRIMERS FOR BIOLOGICAL APPLICA-
TIONS.
Bo Wang
, Esteban Gurzov, Pu Chun Ke, Feng Ding
2692-Pos
Board B69
PHOSPHORYLATION MODIFIES COUPLING OF THE MEMBRANE DOMAINS
AND NBD1 OF FULL LENGTH CFTR.
Stephanie Chin
, Mohabir
Ramjeesingh, Paul Eckford, Christine E. Bear
2693-Pos
Board B70
A FUSION PROTEIN OF P53 PEPTIDE AND MDMX AS AN EFFICIENT MOD-
EL FOR SCREENING OF ANTICANCER PRODRUGS WITH FLUORESCENCE
SPECTROSCOPY. Rong Chen, Lingyun Qin,
Zheng Su
Enzymes Function, Cofactors, and Post-
translational Modifications
(Boards B71 - B92)
2694-Pos
Board B71
EDUCATION TRAVEL AWARDEE
IMPULSIVE ENZYMES: A NEW FORCE IN MECHANOBIOLOGY.
Krishna
Kanti Dey
, Ayusman Sen
2695-Pos
Board B72
DISSECTING PROTON DELOCALIZATION AND THE ELECTROSTATIC CON-
TRIBUTION TO CATALYSIS IN AN ENZYME’S HYDROGEN BOND NETWORK
WITH UNNATURAL AMINO ACIDS.
Yufan Wu
, Steven G. Boxer
2696-Pos
Board B73
VIBRATIONAL STARK EFFECTS FOR DIVERSE CARBONYL PROBES APPLIED
TO THE RE-INTERPRETATION OF IR AND RAMAN DATA IN TERMS OF
ELECTRIC FIELDS AT ENZYME ACTIVE SITES.
Samuel H. Schneider
, Steven
G. Boxer
2697-Pos
Board B74
COMPUTATIONAL STUDY ON THE CATALYTIC EFFECT OF THE MAGNESIUM
IONS IN THE MECHANISM OF DNA POLYMERASES.
Ricardo A. Matute
,
Arieh Warshel
2698-Pos
Board B75
THE EFFECT OF MAGNESIUM ION CONCENTRATION ON THE NUCLEOTIDE
SPECIFICITY AND FIDELITY OF HIV-1 REVERSE TRANSCRIPTASE.
Shanzhong
Gong
, Kenneth Johnson
2699-Pos
Board B76
EDUCATION TRAVEL AWARDEE
THE ROLE OF PHOSPHORYLATION AND ACETYLATION OF TFAM IN DNA
BINDING REGULATION USING SINGLE-MOLECULE MANIPULATION AND
FLUORESCENCE MICROSCOPY.
Maryam Hashemi Shabestari
, Graeme A.
King, Wouter H. Roos, Carolyn K. Suzuki, Gijs J. L. Wuite
2700-Pos
Board B77
EDUCATION TRAVEL AWARDEE
NEW INSIGHT INTO THE CATALYTIC AND INHIBITION MECHANISM OF THE
HUMAN ACYL PROTEIN THIOESTERASE.
Martina Audagnotto
, Sylvia Ho,
Patrick Sandoz, Nicole Andenmatten, Gisou van der Goot, Matteo Dal
Peraro