172 / 266
W
E
D
N
E
S
D
A
Y
145
2728-Pos
Board B105
TAU MEDIATES WIDELY-SPACED MICROTUBULE BUNDLES THROUGH
LOCAL POLYION ATTRACTIONS AT THE MIDPLANE LAYER: A NOVEL, FUNC-
TIONAL MECHANISM FOR INTRINSICALLY DISORDERED PROTEINS.
Peter
J. Chung
, Chaeyeon Song, Joanna Deek, Herbert P. Miller, Youli Li, Leslie
Wilson, Stuart C. Feinstein, Cyrus R. Safinya
2729-Pos
Board B106
EDUCATION TRAVEL AWARDEE
Aβ FIBRILS ACT AS AQUEOUS PORES: A MOLECULAR DYNAMICS
STUDY.
Sachin R. Natesh
, Stephen C. Meredith, Tobin R. Sosnick, Karl F.
Freed, Esmael J. Haddadian
2730-Pos
Board B107
DANCING WITH STRINGS: THE CONFORMATIONAL DYNAMICS OF VQIXXK
MOTIFS WITHIN TAU PROTEIN IN MONOMER, FIBRIL AND HYPER-PHOS-
PHORYLATED FILAMENT STATES.
Buyong Ma
, Guanghong Wei, Jie Zhen,
Ruth Nussinov
2731-Pos
Board B108
THE CONFORMATION OF Aβ-PEPTIDE AGGREGATES ON 2D SURFACES IS
DIFFERENT THAN IN SOLUTION: A MOLECULAR DYNAMICS STUDY. Sachin
R. Natesh, Kark F. Freed,
Esmael J. Haddadian
2732-Pos
Board B109
TAU BINDS TO MULTIPLE TUBULIN DIMERS WITH HELICAL STRUC-
TURE.
Xiaohan Li
, Jacob A. Culver, Elizabeth Rhoades
2733-Pos
Board B110
THE DISPARATE EFFECTS OF TWO MOLECULAR CHAPERONES ON TAU
AMYLOID FORMATION.
Hannah E.R. Baughman
, Amanda F. Clouser,
Rachel E. Klevit, Abhinav Nath
2734-Pos
Board B111
BINDING-ACTIVATED SUPERRADIANT PROBES FOR AMYLOID IN SOLU-
TION AND TISSUE.
Patrick Donabedian
, Nicole Maphis, Shanya Jiang,
Kiran Bhaskar, David Whitten, Eva Chi
2735-Pos
Board B112
AMYLOID AGGREGATION OF AMYLIN: GAIN OF FUNCTION ALONG AG-
GREGATION PATHWAY?
Anoop Rawat
, Debanjan Bhowmik, Barun Kumar
Maity, Sudipta Maiti
2736-Pos
Board B113
AMYLOID-β(1-42)OLIGOMER MODELS DEVELOPED USING COMBINED
SOLID STATE NMR AND SEQUENCE SPECIFIC HYDROXYL RADICAL FOOT-
PRINTING DATA.
Alexandra Klinger
, Cong Guo, Huan-Xiang Zhou, Anant
Paravastu, Janna Kiselar, Andrew J. Nix, Terrone L. Rosenberry
Investigating the Properties of Intrinsically
Disordered Proteins (IDP)
(Boards B114 - B140)
2737-Pos
Board B114
NMR INVESTIGATION OF CALMODULIN INDUCED FOLDING IN THE REGU-
LATORY DOMAIN OF CALCINEURIN.
Dinesh K. Yadav
2738-Pos
Board B115
PROTEIN DESIGN FOR DECREASED DISORDER: SHERP AS AN EXEMPLAR
PROTEIN.
Elliot Drew
, David T. Jones, B.A. Wallace
2739-Pos
Board B116
STRUCTURAL MODELS OF AN INTRINSICALLY DISORDERED PROTEIN
ADAPTED FOR BACTERIAL SECRETION. Darragh Patrick O’Brien, Belen
Hernandez, Dominique Durand, Veronique Hourdel, Ana Cristina
Sotomayor Pérez, Patrice Vachette, Mahmoud Ghomi, Julia
Chamot-Rooke, Daniel Ladant, Sébastien Brier,
Alexandre Chenal
2740-Pos
Board B117
MULTI-COLOR SINGLE MOLECULE FRET STUDY OF INTRINSICALLY DISOR-
DERED PROTEIN BINDING.
Hoi Sung Chung
, Fanjie Meng, Jae-Yeol Kim,
John M. Louis
2741-Pos
Board B118
CHARACTERIZATION OF AN INTRINSIC DISORDER DOMAIN AND FUNC-
TIONAL ACTIVITY OF CHIZ MEMBRANE PROTEIN FROMMYCOBACTE-
RIUM TUBERCULOSIS.
Cristian A. Escobar
, Riqiang Fu, Timothy A. Cross
2742-Pos
Board B119
EXPERIMENTAL POLYPROLINE II PROPENSITIES DESCRIBE SEQUENCE-
DEPENDENT VARIABILITY IN THE HYDRODYNAMIC SIZE OF INTRINSICALLY
DISORDERED PROTEINS.
Steven T. Whitten
2743-Pos
Board B120
RESCUING THE OVER-COLLAPSE OF INTRINSICALLY DISORDERED PRO-
TEINS USING A FORCE FIELD DERIVED BY A NEW PARADIGM.
Davide
Mercadante
, Sigrid Milles, Gustavo Fuertes, Dmitri Svergun, Edward A.
Lemke, Frauke Gräter
2744-Pos
Board B121
PROTEOMIC AND BIOPHYSICAL ANALYSIS OF POLAR TRACTS.
Kiersten M.
Ruff
, Alex S. Holehouse, Mary G.O. Richardson, Rohit V. Pappu
2745-Pos
Board B122
SINGLE-MOLECULE DISSECTION OF THE CONFORMATIONS, DYNAMICS
AND BINDING OF THE DISORDERED 4E-BP2 PROTEIN.
Zhenfu Zhang
, Alaji
Bah, Hamda Sajjad, Julie D. Forman-Kay, Claudiu C. Gradinaru
2746-Pos
Board B123
LC8 MOTIF RECOGNITION: INSIGHTS FROM THE LC8-CHICA COM-
PLEX.
Sarah Clark
2747-Pos
Board B124
NMR-BASED MOLECULAR VIEW OF THE BIOLOGY AND BIOPHYSICS OF
WIP, AN INTRINSICALLY DISORDERED PROTEIN. Eva Rozentur-Shkop,
Hadassa Shaked,
Jordan Chill
2748-Pos
Board B125
EDUCATION TRAVEL AWARDEE
DYNAMICS OF CONTACT FORMATION IN DISORDERED POLYPEPTIDES.
Gül H. Zerze
, Robert B. Best, Jeetain Mittal
2749-Pos
Board B126
CHEMICAL PERTURBATION OF AN INTRINSICALLY DISORDERED REGION
OF TFIID DISTINGUISHES DE NOVO TRANSCRIPTION INITIATION FROM RE-
INITIATION.
Zhengjian Zhang
, Zarko Boskovic, Mahmud Hussain, Wenxin
Hu, Carla Inouye, Angela Koehler, Stuart Schreiber, Robert Tjian
2750-Pos
Board B127
RNA-BINDING DOMAIN DISORDER MODULATES THE RNA DESTABILIZING
ACTIVITY IN THE TTP FAMILY OF PROTEINS. Laura M. Deveau,
Francesca
Massi
2751-Pos
Board B128
PROBING THE CONFORMATIONAL ENSEMBLE OF A BACTERIAL ANTI-
TOXIN THROUGH MOLECULAR DYNAMICS SIMULATIONS AND MASS
SPECTROMETRY.
Virginia M. Burger
, Albert Konijnenberg, Alexandra
Vanderwelde, Frank Sobott, Remy Loris, Collin M. Stultz
2752-Pos
Board B129
THE ROLE OF INTRINSIC DISORDER IN THE MOLECULAR MECHANISM OF
NUCLEAR TRANSPORT.
Laura K. Maguire
, Kathryn Wall, Geoff
Armstrong, Kaushik Dutta, Samuel Sparks, Deniz B. Temel, Alia Kamal,
Jaclyn Tetenbaum-Novatt, Michael P. Rout, David Cowburn, Loren Hough
2753-Pos
Board B130
ELUCIDATING THE MECHANISM OF RECOGNITION AND BINDING OF
PROTEIN KINASE INHIBITOR BY PROTEIN KINASE A USING NMR AND
FLUORESCENCE SPECTROSCOPY.
Geoffrey Li
, Cristina Olivieri, Matthew
Neibergall, Jonggul Kim, Susan Taylor, Joseph Muretta, Gianluigi Veglia