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Anna Costa, Adriaan P IJzerman, Philipp Kügler, Eugen Timin, Godfrey
Smith, Steffen Hering
2598-Plat
2:30 pm
SOMATIC MOSAICISM OF NOVEL SCN5A MUTATION IN PURKINJE SYSTEM
(PS) MAY UNDERLIE 2:1 BLOCK IN AN INFANT WITH LONG QT SYNDROME
(LQTS).
Joseph K. Yu
, Patrick M. Boyle, Thomas O’Hara, James R. Priest,
Euan Ashley, Natalia A. Trayanova
2599-Plat
2:45 pm
THE VOLTAGE-GATED POTASSIUM CHANNEL KV1.3 AS A TARGET FOR
INHIBITING DETRIMENTAL M1 MICROGLIA FUNCTIONS. Yi-Je Chen, Hai
M. Nguyen, Izumi Maezawa, Lee-Way Jin,
Heike Wulff
Platform
Protein Plasticity & Binding
1:00 pm - 3:00 pm, Room 515B
Co-Chairs
Margaret Cheung, University of Houston
Oliver Fisette, Ruhr-University Bochum, Germany
2600-Plat
1:00 pm
A STRUCTURAL CHARACTERIZATION OF THE KV7.2-KV7.3 M CHANNEL
PROXIMAL C-TERMINUS/CAM COMPLEX.
Roi Strulovich
, William
Tobelaim, Bernard Attali, Joel A. Hirsch
2601-Plat
1:15 pm
LESSONS IN PROTEIN DESIGN FROM COMBINED EVOLUTION AND CON-
FORMATIONAL DYNAMICS.
Margaret S. Cheung
, Swarnendu Tripathi, M.
N. Waxham, Yin Liu
2602-Plat
1:30 pm
IN SILICO IDENTIFICATION OF BINDING SITES RESPONSIBLE FOR SPE-
CIES SPECIFICITY ON HUMAN CD81 AND HEPATITIS C VIRUS E2 PROTEIN.
Chun-Chun Chang
, Hao-Jen Hsu, Je-Wen Liou
2603-Plat
1:45 pm
SINGLE-MOLECULE EXPERIMENTS TO RESOLVE STRUCTURAL AND
MECHANICAL PROPERTIES OF CONDENSIN.
Jorine Eeftens
, Allard Katan,
Marc Kschonsak, Markus Hassler, Essam Dief, Liza de Wilde, Christian
Haering, Cees Dekker
2604-Plat
2:00 pm
PROTEIN COMPLEXES FROMMD SIMULATIONS: THE ROPE-PULLING
GAME OF TAPASIN AND HISTOCOMPATIBILITY MOLECULES.
Olivier
Fisette
, Lars V. Schäfer
2605-Plat
2:15 pm
REMEDIAL SYNERGISTIC CONCOCTION OF β-CYCLODEXTRIN AND NATU-
RALLY OCCURRING POLYPHENOLS TARGETING α-SYNUCLEIN AGGREGA-
TION UNDER CELL MIMICKING CONDITIONS.
Saurabh Gautam
, Pramit K.
Chowdhury
2606-Plat
2:30 pm
CONFORMATIONAL CHANGE IN THE ECTODOMAIN OF THE AMYLOID
PRECURSOR PROTEIN IN RESPONSE TO PROTEOLYTIC PROCESSING: THE
RANDOM COIL REGIONS MATTER.
Clare Peters-Libeu
2607-Plat
2:45 pm
THE NON AMYLOID-β COMPONENT (NAC) OF HUMAN α-SYNUCLEIN
OLIGOMERS INDUCES THE FORMATION OF NEW Aβ OLIGOMERS:
INSIGHT INTO THE MOLECULAR INTERACTIONS THAT LINK PARKINSON’S
DISEASE AND ALZHEIMER’S DISEASE.
Yoav Atsmon-Raz
, Yifat Miller
Platform
Micro- and Nanotechnology
1:00 pm - 3:00 pm, Room 501ABC
Co-Chairs
Nicholas Fitzkee, Mississippi State University
Meni Wanunu, Northeastern University
2608-Plat
1:00 pm
HOW DO NANOPARTICLE SIZE AND PROTEIN CHARGE AFFECT GOLD
NANOPARTICLE-PROTEIN INTERACTIONS?
Nicholas C. Fitzkee
, Ailin
Wang, Karen E. Woods, Randika Perera
2609-Plat
1:15 pm
BIOINTERACTIONS OF ULTRASMALL GOLD NANOPARTICLES: INFLUENCE
OF NANOPARTICLE SIZE AND SURFACE CHEMISTRY. Luiza L. Knittel, Sergio
A. Hassan, Maria A. Aronova, Peter Schuck, Richard D. Leapman,
Alioscka
A. Sousa
2610-Plat
1:30 pm
TOWARDS A “GREEN” ANTIMICROBIAL THERAPY: STUDY OF GRAPHENE
NANOSHEETS INTERACTION WITH HUMAN PATHOGENS.
Valentina
Palmieri
, Massimiliano Papi, Francesca Bugli, Mariacarmela Lauriola,
Claudio Conti, Gabriele Ciasca, Giuseppe Maulucci, Maurizio Sanguinetti,
Marco De Spirito
2611-Plat
1:45 pm
TRACKING SINGLE-PARTICLE ROTATION DURING MACROPHAGE UPTAKE.
Lucero Sanchez
, Yan Yu
2612-Plat
2:00 pm
PEPTIDE TRANSLOCATION THROUGH SINGLE LYSENIN CHANNELS.
Nisha
Shrestha
, Sheenah Bryant, Xinzhu Pu, Paul Carnig, Juliette Tinker, Charles
Hanna, Daniel Fologea
2613-Plat
2:15 pm
NANOPORE ZERO-MODE WAVEGUIDES FOR DNA SEQUENCING AND
BEYOND. Joseph Larkin, Robert Y. Henley, Jonas Korlach,
Meni Wanunu
2614-Plat
2:30 pm
CARBON NANOTUBE PORINS: BIOMIMETIC MEMBRANE PORE CHANNELS
FOR NANOFLUIDIC STUDIES.
Aleksandr Noy
2615-Plat
2:45 pm
IMPROVING DNA SEQUENCING WITH NANOPORE MSPA.
Henry
Brinkerhoff
Platform
Membrane Receptors and Signal Transduction
1:00 pm - 3:00 pm, Room 511ABC
Co-Chairs
Diane Lidke, University of NewMexico
Christian Sieben, Humboldt-University Berlin, Germany
2616-Plat
1:00 pm
THE DYNAMICS AND LOCALIZATION OF THE EPIDERMAL GROWTH FAC-
TOR RECEPTOR (EGFR) ON LIVE CELL PLASMA MEMBRANE STUDIED BY
ITIR-FCS.
Shuangru Huang
, Nirmalya Bag, Thorsten Wohland
2617-Plat
1:15 pm
PROBING THE NON-GENETIC CELL-TO-CELL HETEROGENEITY IN EGFR-
MEDIATED MAPK ACTIVATION BY SUPER-RESOLUTION MICROSCOPY.
Oana Coban
2618-Plat
1:30 pm
INFLUENZA A VIRUSES USE MULTIVALENT SIALIC ACID CLUSTERS FOR
CELL BINDING AND RECEPTOR ACTIVATION.
Christian Sieben
, Suliana
Manley
2619-Plat
1:45 pm
THE BINDING LIFETIME OF SYK KINASE TO THE IMMUNE RECEPTOR FCεRI