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10

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D

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10:45 am–12:45 pm

Symposium: New and Notable

Petree Hall C

Co-Chairs:

Vasanthi Jayaraman, University of Texas Health Science Center, and E. Michael Ostap, University of Pennsylvania

STRUCTURE OF A TRPV2 ION CHANNEL,

Seok-Yong Lee

CRYO-EM STRUCTURE OF A MICRONUTRIENT TRANSPORTER WITH UNUSAUL ARCHITECTURE.

Filippo Mancia

STRUCTURAL DYNAMICS OF K CHANNEL GATING REVEALED BY SINGLE MOLECULE FRET.

Colin Nichols

THE MOTIONS AND INTERACTIONS IN MISMATCH REPAIR TAGET SEARCH DYNAMICS ARE REVEALED BY LIVE-CELL

SINGLE-MOLECULE MICROSCOPY.

Julie Biteen

INTEGRATIVE STRUCTURAL BIOLOGY OF TETRAHYMENA TELOMERASE.

Juli Feigon

INTRINSICALLY DISORDERED PROTEINS AS PHYSICAL DRIVERS OF MEMBRANE TRAFFIC.

Jeanne C. Stachowiak

FLOPPY BUT NOT SLOPPY: DECODING PLASTICITY IN THE DARK PROTEOME OF THE NUCLEAR TRANSPORT MACHINERY.

Edward Lemke

10:45 am–12:45 pm

Symposium: Computational and Experimental Approaches to Protein Design

Petree Hall D

Chair:

Rama Ranganathan, University of Texas, Southwestern

MAPPING CONSTRAINTS ON PROTEIN EVOLUTION

. Jesse Bloom

UNCOVERING AND REPROGRAMMING G PROTEIN COUPLED RECEPTOR SIGNALING.

Patrick Barth

DESIGNING PEPTIDE INHIBITORS OF ANTI-APOPTOTIC BCL-2 FAMILY PROTEINS

. Amy E. Keating

PROTEIN MECHANICS: THE LINK BETWEEN STRUCTURE AND FUNCTION.

Rama Ranganathan

10:45 am–12:45 pm Platform: Cryo-Electron Microscopy

Room 502A

10:45 am–12:45 pm Platform: Cell Mechanics, Mechanosensing, and Motility I

Room 502B

10:45 am–12:45 pm Platform: TRP Channels

Room 515A

10:45 am–12:45 pm Platform: Protein Assembly and Function

Room 515B

10:45 am–12:45 pm Platform: Membrane Active Peptides and Toxins

Room 501ABC

10:45 am–12:45 pm Platform: Cardiac Smooth and Skeletal Muscle Electrophysiology

Room 511ABC

11:30 am–1:00 pm Undergraduate Student Pizza "Breakfast"

Room 406AB

11:30 am–5:00 pm Colleges in the Community Day

Room 406AB

12:00 pm–1:00 pm International Travel Awardee Luncheon

Room 404AB

12:00 pm–1:00 pm Career Center Workshop

Room 518

Creating and Using an Effective CV/Résumé

12:15 pm–2:15 pm Public Affairs Committee Meeting

Room 506

1:00 pm–2:30 pm The World Outside the Lab: Many Ways to Use Your PhD Skills in Industry

Room 403A

1:00 pm–3:00 pm Graduate & Postdoc Institution Fair

West Hall

1:45 pm–3:00 pm Snack Break

West Hall

1:45 pm–3:45 pm Poster Presentations and Late Posters

West Hall

2:00 pm–3:30 pm Teaching Science Like We Do Science

Room 408A

2:30 pm–3:30 pm Career Center Workshop

Room 518

Networking for Nerds

2:30 pm–4:00 pm Transparency, Reproducibility, and the Progress of Science

Room 411

3:30 pm–5:00 pm Early Careers Committee Meeting

Room 506

4:00 pm–5:00 pm Career Center Workshop

Room 518

Ten Tough Industrial Interview Questions (and Ten Pretty Good Responses)

4:00 pm–6:00 pm

Symposium: Signaling Complexes and Dynamics

Petree Hall C

Chair:

Hao Wu, Harvard Medical School

STRUCTURAL ELUCIDATION OF INNATE IMMUNITY

. Hao Wu

MECHANISM OF JAK2 ACTIVATION BY THE ARCHETYPE CLASS I CYTOKINE RECEPTOR, THE GROWTH HORMONE RECEPTOR.

Andrew J. Brooks

MECHANISM AND FUNCTIONS OF PLATELET MECHANOSENSING.

Renhao Li

CONFORMATIONAL PLASTICITY AND DRUGGABILITY OF MEMBRANE-BOUND K-RAS.

Alemayehu A. Gorfe