61 / 266
34
S
U
N
D
A
Y
Voltage-gated K Channels and Mechanisms
of Voltage Sensing and Gating I
(Boards B302 - B331)
522-Pos
Board B302
WATER TRANSPORT ACROSS THE VOLTAGE SENSOR OF SHAKER K-CHAN-
NELS DURING ACTIVATION.
Ignacio Diaz-Franulic
, David Naranjo
523-Pos
Board B303
HYDRATION AND THE ELECTRIC FIELD IN THE VOLTAGE SENSING DOMAIN
OF THE KV1.2 CHANNEL: QUANTUM CALCULATIONS SHOW S4 DOESN’T
MOVE, BUT WATER AND PROTONS MOVE. Alisher M. Kariev,
Michael E.
Green
524-Pos
Board B304
WATER AND A PROTON SHIFT BETWEEN A TYROSINE AND A GLUTAMATE
ARE TWO KEYS TO GATING IN KV1.2; A HYPOTHESIS BASED ON QUAN-
TUM CALCULATIONS: THE SENSOR IS DYNAMIC, BASED ON HYDROGEN
BOND REARRANGEMENTS, PRINCIPALLY IN WATER ROTATIONAL DEGREES
OF FREEDOM, PLUS A PROTON PATHWAY.
Alisher M. Kariev
, Michael E.
Green
525-Pos
Board B305
STRUCTURAL INSIGHTS OF THE CALCIUMMEDIATED REORGANIZATION
OF THE CALMODULIN/KV7.2 CHANNEL COMPLEX.
Alvaro Villarroel
,
Ganeko Bernardo-Seisdedos, Alessandro Alaimo, Carolina Gomis-Perez,
Araitz Alberdi, Covadonga Malo, Pilar Areso, Oscar Millet
526-Pos
Board B306
CID TRAVEL AWARDEE
BIOCHEMICAL ANALYSIS OF THE REGULATION OF KV7 CHANNELS BY
PIP2 AND CALMODULIN.
Crystal R. Archer
, Benjamin T. Enslow, Mark S.
Shapiro
527-Pos
Board B307
CENTRIN 4 IS A BINDING PARTNER OF RAT EAG1 K
+
CHANNELS. Po-Hao
Hsu,
Chih-Yung Tang
, Chung-Jiuan Jeng
528-Pos
Board B308
GATING CURRENT MODELS COMPUTED WITH CONSISTENT INTERAC-
TIONS. Tzyy-Leng Horng,
Robert S. Eisenberg
, Chun Liu, Francisco
Bezanilla
529-Pos
Board B309
INTERNATIONAL TRAVEL AWARDEE
A MOLECULAR SUBSTRATE FOR LONG QT IN HIV PATIENTS: TAT PROTEIN
REDUCES IKR IN HUMAN INDUCED PLURIPOTENT STEM CELLS-DERIVED
CARDIOMYOCYTES.
Zeineb Es-Salah-Lamoureux
, Mariam Jouni, Nadjet
Belbachir, Marine Gandon-Renard, Bruno Beaumelle, Isabelle Baró,
Flavien Charpentier, Kazem Zibara, Patricia Lemarchand, Nathalie Gaborit,
Gildas Loussouarn
530-Pos
Board B310
CHARACTERIZATION OF A FAST VOLTAGE-SENSING PROTEIN USING
VOLTAGE-CLAMP FLUOROMETRY.
Ferenc Papp
, Jaime Smith, Orsolya
Szilagyi, Tsg-Hui Chang, Kenton J. Swartz
531-Pos
Board B311
PATCH-CLAMP FLUOROMETRY BASED DETERMINATION OF RELATIVE ION
PERMEABILITY FOR HCN CHANNELS. Khade L. Grant, Chang Liu,
Lei Zhou
532-Pos
Board B312
DISTANCE-RESOLVING VOLTAGE CLAMP FLUOROMETRY (DRVCF)
QUANTIFIES INTRAMOLECULAR TRANSITIONS IN THE HUMAN BK AND
CI-VSP VOLTAGE SENSORS UNDER PHYSIOLOGICALLY-RELEVANT CONDI-
TIONS.
Antonios Pantazis
, Riccardo Olcese
533-Pos
Board B313
EFFECT OF SMALL-MOLECULES ON S4 MOVEMENT AND GATING OF NOR-
MAL AND MUTATED IKM CHANNELS.
Rene Barro-Soria
534-Pos
Board B314
PROBING THE S4-S5 LINKER MOVEMENT DURING ACTIVATION IN KV
CHANNELS.
Tanja Kalstrup
, Rikard Blunck
535-Pos
Board B315
THE EFFECT OF MEMBRANE CHOLESTEROL CONTENT ON THE GATING
MECHANISM OF VOLTAGE GATED POTASSIUM CHANNELS. Pal Pap, Zoltan
Petho, Gyorgy Panyi,
Zoltan Varga
536-Pos
Board B316
THE CONSTRICTED FILTER CONFORMATION: A GENERAL PROPERTY FOR
C-TYPE INACTIVATION OF DIFFERENT POTASSIUM CHANNELS?
Jing Li
,
Jared Ostmeyer, Mikolai Fajer, Benoit Roux
537-Pos
Board B317
A RECIPROCAL VOLTAGE SENSOR-TO-PORE COUPLING IN C-TYPE INACTI-
VATION.
Luca Conti
, Jakob Renhorn, Anders Gabrielsson, Fredrik Tures-
son, Sara Liin, Erik Lindahl, Fredrik Elinder
538-Pos
Board B318
DYN-MEDIATED INTERNALIZATION OF KCNQ1/KCNE1 CHANNELS UNDER
SUSTAINED CPKC ACTIVATION.
Xiaorong Xu Parks
, Elsa Ronzier, Jin O-
Uchi, Coeli M. Lopes
539-Pos
Board B319
TRAFFICKING DEFICIENT KV11.1 (HERG) MUTATIONS LINKED TO LONG QT
SYNDROME LOCALIZE TO DIFFERENT ENDOPLASMIC RETICULUM SUB-
COMPARTMENTS. Jennifer L. Smith, Corey L. Anderson, Criag T. January,
Brian Delisle
540-Pos
Board B320
INTERACTIONS BETWEEN THE C-LINKER AND THE S4-S5 LINKER MEDIATE
GATING IN CNGA1 CHANNELS. Manuel Arcangeletti, Monica Mazzolini,
Claudio Anselmi,
Debora Grosa
, Sourav Maity, Arin Marchesi, Luisa Na-
politano, Vincent Torre
541-Pos
Board B321
ENGINEERING SUBUNIT AND NONSENSE SUPPRESSION STOICHIOMETRY
IN POTASSIUM CHANNELS.
John D. Lueck
, Adam L. Mackey, Jason D.
Galpin, Christopher A. Ahern
542-Pos
Board B322
SLACK CHANNELS NULL MICE EXHIBIT INCREASED SENSITIVITY TO ME-
CHANICAL STIMULI BUT NORMAL RESPONSE TO THERMAL STIMULI. Ran
Wang, Ying Song, Jie Xu, Meng-Jiao Tan, Tian-Yu Cao, Shun-Heng Gao,
Meng-Han Sun, Fei-Fei Zhang,
Zhe Zhang
543-Pos
Board B323
EQUILIBRIUM FLUCTUATION RELATIONS FOR GATING CHARGE IN VOLT-
AGE SENSITIVE MEMBRANE PROTEINS: A MICROSCOPIC CAPACITOR
MODEL APPROACH.
ILSOO KIM
, Arieh Warshel
544-Pos
Board B324
MEMBRANE FORCES REGULATE VOLTAGE SENSOR MOVEMENT. Mehdi
Torbati, Vikash Chaurasia, Kranthi Mandadapu,
Ashutosh Agrawal
545-Pos
Board B325
GATING CHARGE CALCULATIONS: PROBING VOLTAGE-SENSING PRO-
TEINS THROUGH COMPUTATIONAL ELECTROPHYSIOLOGY.
Jan-Philipp
Machtens
, Rodolfo Briones, Bert L. de Groot, Christoph Fahlke
546-Pos
Board B326
COMPUTATIONAL CHARACTERIZATION OF CONFORMATIONAL TRANSI-
TIONS IN THE VOLTAGE-SENSING DOMAIN OF CI-VSP.
Rong Shen
, Qufei Li,
David Medovoy, Yilin Meng, Benoît Roux, Eduardo Perozo
547-Pos
Board B327
MODELING OF THE SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTAS-
SIUM CHANNEL AND CARDIAC ALTERNANS.
Matthew Kennedy
, Donald
M. Bers, Nipavan Chiamvimonvat, Daisuke Sato