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Langen et al. IJROBP 70:1272-80. 2008

APBI with helical Tomotherapy

- two plans for 10 patients (standard helical and

fixed beam (topotherapy

))

- NSABP B-39/RTOG 0413 guidelines for target coverage and normal tissue dosimetry

Helical

Topotherapy

Target

V100 (%)

95

95

Uninvolved ipsilat. breast

V50 (%)

30

40

Ipsilat. lung

V10Gy (%)

17

10

Heart (left sided)

V2Gy (%)

13

5

The

conformation

of the prescription dose to the target was greater for

helical deliveries

,

while the

ipsilateral lung and heart

dose were significantly reduced for the

topotherapy

plans.

Topotherapy beams