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#6,

day 125

Control

#21, day 125

Treated

Nawroth et al. R&O 97: 143-148, 2010

Purpose:

Does targeting

TNFα prevent

radiation

induced fibrosis

?

Therapy

45 Gy / 1 fr to hind leg of mice

Test: Nanoparticles targeting TNFα

injected intraperitoneally

Model: Leg contracture model