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Moon et al, R&O 2009

50% of prescribed dose to non-target breast:

Proton mean 16.5 %

Tomo mean 22.8%

IMRT mean 33.3%

3D CRT mean 40.9%

Average lung receiving 20% of prescribed dose

Proton 0.4%

IMRT 2.3%

3D CRT 6.0%

Tomo 14.2%

P<0.001

P<0.001

Comparison of 4 different external beam RT techniques:

3D CRT, IMRT, helical Tomotherapy, proton beam therapy

N=30 patients

Target

Non-target breast

Lung