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Comparison of effective target volume between MammoSite

and 3D CRT

Problem: different cavity expansion used depending on technique, MammoSite

1.0 cm, 3D CRT 1.5 cm. Previously stated that this is effectively equivalent.

But is that true?

10 pts treated with MammoSite, CT scan before and after balloon implantation

Deformable registration was used to deform the MammoSite CTV onto the

balloonless CT scan. This takes into account asymmetric cavity and that

tissue around the MammoSite is stretched during inflation of balloon

Shaitelman et al, IJROBP, 2012

MammoSite with CTV, 1.0cm margin

Effective CTV generated by deforming the MammoSite

CTV onto the pre-MammoSite CT. Arrows indicate

anatomical features for accuracy

CTV effective