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Average heart receiving 20% and 10% of prescribed dose in left-sided pts

(N=19):

Proton

0% 0%

IMRT

1.2% 4.0%

3D CRT

1.5% 3.1%

Tomo

8.0% 19.4%

Time consumption: beam-on time <5 min (3D CRT, IMRT, proton)

For Tomo therapy beam-on time is 10-15 min

Comparison of 4 different external beam RT techniques:

3D CRT, IMRT, helical Tomotherapy, proton beam therapy

Moon et al, R&O 2009

P<0.001

Conclusion:

All 4 techniques show acceptable coverage of PTV breast.

However, effective sparing of non-target breast was

achieved at the cost of considerable dose exposure to the

breast, heart and lung in Tomotherapy