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Application variation in fractionated HDR GYN BT

(Kirisits et al. 2006)

Mean differences between single plan for all implantations to

individual plan for each implantation

5 9 G f D CTV

. y or

90

HR

(14 % for BT dose only, 7 % including EBRT)

Much higher compared to interfraction study:

BT applied already during EBRT! (shrinkage)