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Difference between models and simulated (TCP
and NTCP) dose-response
dose
systematic
random
(Gy EQD2
a/b
=
10Gy
)
U
s
5% U
r
10% U
r
20%
D
TCP
75
1.0% -0.1% -0.3%
90
0.8% -0.1% -0.3%
(Gy EQD2
a/b
=
3Gy
)
U
s
5% U
r
10% U
r
20% U
r
30%
D
NTCP
65
0.5%
0.1% 1.1% 2.3%
75
1.4%
0.2% 1.6% 3.2%
“Can reduction of uncertainties in cervix cancer brachytherapy potentially
improve clinical outcome?” Nesvacil et al. 2016, submitted to R&O