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reducing random uncertainties can change the slope of the
dose-response relationship observed in a patient cohort
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Online image-based treatment delivery verification (reduce time
between treatment simulation and treatment)
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Advanced in vivo treatment dose verification
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reduction of large systematic uncertainties should be a goal
for OAR and target structures
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Contouring uncertainties
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Large dose calculation uncertainties (see Luc‘s presentation on
clinical outcome vs. dose calculation algorithm)
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Systematic OAR filling changes during treatment (filling
protocols!)