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Preconditions:

Complete 3D anatomy model:

Targets (GTVs), CTV/PTV, OARs

Implanted catheters/applicators

Rules/selection of source dwell positions

Desired dose distribution

Morphology

= ,

= σ

=

,

. .

= ?

Topography

Dosimetric

Result/Aims

( )

Inverse Optimisation

and Planning