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Low dose Objective for PTV/GTVs
D
L
= D
V
for V
100%
High dose Objective for PTV/GTVs
D
H
= D
V
for V
0%
General Form of an
Objective Function
and DVH
Define Dose Window
for Target(s), NT &
OAR(s)
“Desired” Dose
Distribution
Desired Dose Distribution:
Objectives
Objective
Functions
L
=
1
=1
Θ −
−
=
1
=1
Θ −
−
Dose
window
The Norm Factor
p
0 : Volume counting
1 : Linear penalty
2 : Quadratic penalty
Inverse Optimisation and Planning
Transition Function
Θ:
(y) =
0,
∀ < 0
1,
∀ ≥ 0
H