750 / 1224
d
i
j
is the dose at the
j
th
-sampling point for the
i
th
-objective function:
=
=
=
cath
k
ASDP
N
k
N
l
i
jkl
lkK lk
i
j
d Sx
d
1
1
,
2
~
(x)
Catheters Active SDPs
Dwell times
t
lk
?
•
x²
lk
= t
lk
to avoid negative (non-physical) dwell time values
t
lk
•
, can (should) be calculated in a pre-processing step and are then
available in a sense of
a Look-Up-Table
for the optimisation process.
Implementations in this way make optimiser independent of the
dose calculation engine considered (
TG 43, MC, BS, CC, other Engines
)
i
jkl
d
~
Objectives & Objective Functions
Inverse Optimisation
and Planning