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d

i

j

is the dose at the

j

th

-sampling point for the

i

th

-objective function:

 

=

=

=

cath

k

ASDP

N

k

N

l

i

jkl

lkK lk

i

j

d Sx

d

1

1

,

2

~

(x)

Catheters Active SDPs

Dwell times

t

lk

?

lk

= t

lk

to avoid negative (non-physical) dwell time values

t

lk

, can (should) be calculated in a pre-processing step and are then

available in a sense of

a Look-Up-Table

for the optimisation process.

Implementations in this way make optimiser independent of the

dose calculation engine considered (

TG 43, MC, BS, CC, other Engines

)

i

jkl

d

~

Objectives & Objective Functions

Inverse Optimisation

and Planning