763 / 1224
=
1
=1
Θ −
−
=
1
=1
Θ −
−
Objectives & Objective Functions
Low-Objective
D
L
for V
Low
High-Objective
D
H
for V
High
d
i
j
is the Dose at the Sampling Point
j
for
Objective Function i
:
Inverse
Optimisation and
Planning
Define Dose Window
for Target(s), NT & OAR(s)
Objective Functions
Objectives
=
=
=
feasible
k
ASDP
N
k
N
l
i
jkl
lkK lk k
i
j
d Sxb
d
1
1
,
2
~
(x)
Feasible
Catheters
Active
SDPs
Dwell times
t
lk
= x
lk
²
Binary:
Catheter
Selection
Ԧ = න
−∞
+∞
´
− ´
?