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=

=

=

feasible

k

ASDP

N

k

N

l

i

jkl

lkK

lk k

i

j

d Sxb

d

1

1

,

2

~

(x)

Summary –

Inverse Planning

b

∈ ,

& x

HIPO

(in RTPs)

single stepping source

GA

– based (research)

HDR-afterloader

MILP

– based (research)

z.B.

192

Ir

b

∈ ,

& x

∈ ,

IPSA

(in RTPs)

seeds implants

permanent

MIP

-formulations & methods

z.B.

125

I

GA

– based

Catheter/needle

selection

Source dwell time

or seed position

Source strength