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8

10

12

14

16

18

0.0

0.1

0.2

0.3

0.4

0.5

0.6

0.7

0.8

0.9

1.0

1.1

1.2

Normalised Objective Value

Number of Catheters

Aggregated

PTV high

PTV low

Urethra

Rectum

w=10

w=10

Prostate = 25 cm³

Inverse Planning – using

HIPO

=

=

=

feasible

kASDP

N

k

N

l

i

jkl

lk

K lk k

i

j

d Sxb

d

1

1

,

2

~

(x)

     

) ,

, (

1

w t

r f

fw f

M

m

m m

=

=

=

Minimise

w=20

w=5

PTV