1065 / 1851
SCLC/LCNEC: State of the art treatment
Platinum
(either cis or carbo)
combination chemotherapy
(i.e cis/carbo-
etoposide) x 4-6 courses q 3 weeks
“standard of care”
1
st
line therapy for
both
LD and ED
Combined chemotherapy
and thoracic
radiotherapy
(preferably early
concurrent)
standard of care for LD
Possible
role of upfront
surgery
in very limited disease
Second line therapy: Topotecan o CAV or PE-rechallenge based on treatment-free
interval (refractory vs sensitive disease)
PCI
for pts with both
LD or ED
with
good response
to 1
st
line therapy
Thoracic irradiation in ED
?