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National or institutional molecular screening programs in breast
cancer and other advanced solid tumors predictive biomarker
Institution or National
Program
Platform
Cancer(s)
Archival vs
Biopsy
Timeframe
Additional Details
Massachusetts General
Hospital
SNaP Shot
NSCLC, CRC,
Melanoma, Breast
Archival
Ongoing
Includes somatic
mutations in 14
oncogenes. In NSCLC,
additional FISH panel for
ALK rearrangements.
Plan to integrate NGS
technology in near
future.
Dana Farber Cancer
Institute
OncoMap
(Sequenom)
All solid tumors
Archival
Ongoing
$43 million investment
over 5 years. Currently
tests ~470 mutations in
41 genes.
MD Anderson Cancer
Centre
Sequenom
All
Archival
Ongoing
“T9 Program”.
Customized Sequenom
Panel (40+ genes) with
Sanger confirmation.
Plan to screen “Ten
Thousand Tumors”.