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Institution or
National Program
Platform
Cancer(s)
Archival vs
Biopsy
Timeframe
Additional Details
Vanderbilt-Ingram
Cancer Center
SNaPshot
NSCLC,
melanoma, and
breast
Archived Ongoing
SNaPshot profiling of
~40 mutations in
NSCLC and
melanoma. Recently
launched “PI3K”
panel for breast
cancer.
Michigan University
Illumina HiSeq Solid Tumors
Fresh
Biopsies
Ongoing
Plan to perform
whole exome
sequencing for 100
patients per year.
Princess Margaret
Hospital
Sequenom Breast, CRC,
Ovarian, NSCLC,
and phase I
Archival
1Q2012
Customized
Sequenom panel
(~277 mutations in
25 genes). Plan to
integrate NGS
technology in near
future.
National or institutional molecular screening programs in breast
cancer and other advanced solid tumors predictive biomarker