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1999-2001, 23 UK centres: Tumor <5 cm and ≤3 N+ in axillae
(92% lumpectomy, 74% pN0, 64% T<2 cm, 72% only Tam, 15% Tam+CT,
7% RT to axillae)
2215 pts
Endpoints: local control and morbidity
Median follow-up 6.0 years
40 Gy/15 fX, 2.67 Gy/fx
50 Gy/25 fX, 2.0 Gy/fx
Yarnold et al Lancet, 2008