R
A
N
D
O
M
I
Z
T
NACT
5FU/cisplat
45 to 59 Gy
+ 5FU /MMC
N = 644 patients
Intergroup RTOG 98-11
45 to 59 Gy RT
+ 5-FU/CDDP
T2-4
N0
N+