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“High Risk” LGG according to European criteria

477 patients were randomly assigned to receive either 50.4 Gy RT (240) or TMZ (237)

RT vs TMZ in HR LGG: EORTC 22033

Baumert BG et al. Lancet Oncol 2016;17

Median PFS: 46 (RT) vs 39 (TMZ) months

p = 0.22