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Molecular “status” overcomes treatment strategy…

Favourable

Unfavourable

IDH1 mutated

IDH1 wt

1p/19q codeleted

1p/19q NON codeleted

RTOG 9402

Cairncross JG. et al. JCO 2014;32

EORTC 26951

Van den Bent MJ. et al. JCO 2013;31

…can we consider RT + PCV as standard of care ?