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CODEL: Phase III study of RT+ concomitant and adjuvant
TMZ vs RT + adjuvant PCV in patients with 1p/19q codeleted
anaplastic glioma or Low grade glioma
INITIAL DESIGN
R
RT
TMZ
RT + TMZ followed by adjuvant TMZ x 6
Estimated enrollment: 520
Study start date: October 2009
Estimated primary completion date: December 2018
Central pathology
- O/AO
- 1p/19q codeletion
PROPOSED DESIGNED OF REVITALIZED TRIAL
followed by PCV x 6