Diapositive 1

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Take Home Message (Anaplastic gliomas)
 Median survival >10 years
 Benefit from “upfront” sequential RT and CT (PCV regimen)
 RT PCV or PCVRT are both feasible options
 TMZ instead of PCV? No final answer so far (waiting for results from CODEL trial)
A) 1p/19q CODELETED TUMORS
B) NON-CODELETED TUMORS
 Median survival 2-7 years
 RT as current standard for newly diagnosed cases.
 Benefit from adjuvant TMZ (CATNON trial)