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The primary end points were:

a) 2-year progression-free survival (PFS)

b) acute treatment-related toxicity.

No evidence of neurocognitive decline

within the 12-month post-

rdWBRT

follow-up

period. One case of grade 4 neutropenia

57% in the entire population

79% in the patients who received rdWBRT

Shah et al. JCO 2007;25

Feasibility of ”reduced dose” WBRT