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50

Foroudi et al.,

(2011)

27

64Gy in 32f (bladder)

3DCRT,

Plan of the day, 3

plans for 8-32f

V95< 99% in

2.7%

29% reduction in

tissue receiving

>45Gy compared

to conventional

approach

Meijer et al.,

(2012)

20 59.8Gy in 23f (tumour)

46Gy in 23f (bladder)

IMRT

Plan of the day, 6

plans

>95%

appropriately

fractions covered

Foroudi et al.,

(2014)

54

64Gy in 32f (bladder)

3DCRT

Plan of the day, 3

plans for 8-32f

18.4% patients

target at least

once (5.5% f)

outside PTV as

assessed on post

RT CBCT

Vestergaard et

al., (2014)

20

60Gy in 30f (bladder)

48Gy in 30f to (pelvic LN)

IMRT (VMAT)

Plan of the day, 3

plans for 6-30f

30% (185cm

3

)

reduction in

adaptive PTV,

bowel V45Gy

improved by

100cm

3

and

rectal V30

improved by 10%

compared to

non-adaptive

approach

Murthy et al.,

(2016)

44

68Gy in 32f (tumour)

64Gy in 32f (bladder)

55Gy in 32f (pelvic LN)

IMRT

(tomotherapy)

Plan of the day, 3

or 6 plans

Hafeez et al.,

(2016)

20

70Gy in 32f (tumour)

52Gy in 32f (bladder)

IMRT

Plan of the day, 3

plans

D98 > 97% (post

treatment CBCT)