1049 / 1542
HYBRID study
of hypofractionated Bladder Radiotherapy
with or without Image guided aDaptive planning
A multicentre randomised phase II study
51
Group 1:
Standard planning (control)
Planning CT scan post void. Clinical target
volume (CTV): whole bladder plus any area of
extravesical spread.
One 3D conformal plan will be generated with
1.5cm expansion margin.
Pre-treatment Cone Beam CT will be used to
verify CTV coverage.
Group 2:
Adaptive planning (experimental)
Planning CT scan post void.
CTV: whole
bladder plus any area of extravesical spread.
Three 3D conformal plans will be generated:
1. Small; 2. Medium; 3. Large
Pre-treatment Cone Beam CT will be used to
select appropriate plan, this will be confirmed
by a second trained observer.
RANDOMISE
1:1