755 / 1068
Aristotle National UK Trial schema n=920
MRI < 1mm from mesorectal
fascia
Identify potential pt at MDT
Eligibility
Intended post-op chemo policy
Capecitabine CRT (45Gy)
Capecitabine Irinotecan CRT (45Gy)
Surgery
Surgery
Post-op policy
Post-op policy
Primary endpoint 2 year DFS