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Challenges
•
Quantitative recovery from finished product
forms, e.g., beadlets, softgels, etc.
•
Dozens of carotenoids co‐extract from their
botanical sources
A l t
diffi lt t
t f
h
•
na y es are
cu o separa e rom one eac
other, isomers, and metabolites
Existing Methods General
‐
•
HPLC – UV
•
U/HPLC – MS/MS