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Oliver Jäkel
Medical Physics
Tissue changes in MRI post RT: Craniospinal pRT
Treatment
planning
CT and
dose
Changes in fat signal in irradiated part of vertebral bodies,
Distal dose fall off can be visualized – how early ??
Described already in Krejcarek, Yock, et al. IJROBP 2007;68(3):646-649
T1-w MRI
6 months
after pRT
HIT patient
Page 26
Oliver Jäkel
Medical Physics
Planning CT
Post 3fx
Post 5fx
Difference Image (Post 5fx - Post 3fx)
MRI for response assessment during p-RT?
Dose-correlated changes visible
about 10-12 days after start of
treatment!
C Richter et al. Med. Hypoth. 2014
Not in all patients though – to be investigated