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Page 35
Oliver Jäkel
Medical Physics
Analytical approach for uncertainty quantification
and minization in particle therapy
M. Bangert, P. Hennig, U. Oelfke. Phys Med. Biol. 2013
N. Wahl, et al. Phys. Med. Biol. 2017
[Gy]
Probabilistic p-TP for robust optimization
Robust optimization allows for increased probability for coverage,
smaller PTV, higher robustness
Systematic errors: 3.5% Range, 1mm Setup
Random errors: 1mm range, 2mm Setup
Page 36
Oliver Jäkel
Medical Physics
Probabilistic proton dose calculation
accounting for fractionation
•
Random and systematic uncertainties
1 fraction
5
s
103
Work by M. Bangert, et al.
No y t implemented in any commercial TPS