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Page 39

Oliver Jäkel

Medical Physics

DOSE

LET

Planned target

SFUD

LET-Painting

LET Painting for hypoxic tumors

F-MISO PET

C

12

p

C

12

p

Scanning and IMPT offers additional degrees of freedom

for plan optimization (LET, beam width, scan path, …)

Courtesy of N. Bassler et al. (Aarhus)

Page 40

Oliver Jäkel

Medical Physics

Outlook: Helium to replace protons ?

He may replace p’s:

- reduced penumbra

- similar biology

He beams commissioned at HIT in Dec 2013