Esophageal cancer epidemiology
• 7th Leading cause of death
• Incidence in China 20-30 times higher than in USA
or Western Europe
• Age: peak in 6th to 7th decade
• Male/female incidence ratio = 3.5/1
• Squamous cell cancer and adenocarcinoma
represent 95% of cancers
•
SCC most common worldwide
•
Adenocarcinoma
•
Shift to >50% in USA and Western Europe over last 3 decades
•
Obesity, reflux disease, Barretts’s esophagus