Clinical problem
Dysphagia and weight loss
Submucosal spreading
Resectable M0
Pre-op radiochemo + surgery better than surgery (level I)
Surgery alone in selected patients
Unresectable M0 disease
Pre-op radiochemo + surgery
Radiochemo alone
Replacement of radiotherapy by concurrent
radiochemotherapy (level I) was the most important
progress in esophageal cancer over the last 3
decades