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HCC Conclusions (2)

Recent NIRS data suggest unique solu3ons

Large tumor size (≠ PEI, RFA, SBRT)

Loca3on at porta hepa3s (≠ PEI, RFA, surgery)

Cost: 2 frac3ons

Range of applica3on with cura3ve intent

Inoperable or unable to support invasive procedures

Range of size and numbers of tumors

Unresectable disease

HCC near porta hepa3s

Pa3ents on the transplant list

Trials

Hypofrac3onated PBT

Randomized trials against ‘standards’