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Bussink et al. Radiother Oncol, 67: 2003
Hypoxia in solid tumors
Blood vessels (
blue
), exogenous hypoxia marker (pimonidazole,
green
) and
endogenous hypoxia marker (carbonic anhydrase 9,
red
)
Arrows indicate areas with almost no pimonidazole staining but extensive
expression of CA9. CA9 expression is also often found closer to vessels than
pimonidazole, indicating that CA9 is expressed at higher pO2 levels
(magnification 100 x)
human squamous cell
carcinomas of the
oropharynx