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Rectal IMRT

• 45-50.4Gy/25-28# with chemotherapy

• 14 prospective studies

Reduced irradiated bowel volume (V45, V50)

Benefit depends upon bowel proximity to PTV

Some suggest improved acute toxicity

• Minimal late toxicity data

• RTOG 0822: Ph II evaluation of pre-operative

CRT using IMRT with capox

Teoh Clin Oncol 2016;28:93-102