Rectal IMRT
• 45-50.4Gy/25-28# with chemotherapy
• 14 prospective studies
•
Reduced irradiated bowel volume (V45, V50)
•
Benefit depends upon bowel proximity to PTV
•
Some suggest improved acute toxicity
• Minimal late toxicity data
• RTOG 0822: Ph II evaluation of pre-operative
CRT using IMRT with capox
Teoh Clin Oncol 2016;28:93-102