Rectal IMRT
• Ph II evaluation of IMRT-IGRT pre-operative
CRT with SIB
• Prospective study of IMRT use
• 108 patients, 54/12 FU
• 9% ≥G3 late gastrointestinal toxicity
• 4% ≥G3 late urinary toxicity
• 13% ≥G3 any late toxicity
• Good LC, survival
Engels et al, Radiother Oncol 2014;110:155-159