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Cost Functions can be Balanced by

Weight Factors: the Lagrange Function

0

,1

1

1

=

=

=

=

j

M

j

j

M

j

j j

F

L

λ

λ

λ

Combine all goals

to one weighted sum:

…and minimize the Lagrange Function

L

.

ESTRO IMRT course 2016

IMRT optimization: algorithms&cost functions

London April 4th, 2016

-26-

Tuning the weight factors makes all solutions in Solution Space accessible.

Problem: find the right set of weights that produces a dose distribution

as minimizer of

L

which is

`

closest to the intended`

treatment.

j

λ

This is a decision to be made by the user,

not the software