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Parametrisation of the Solution Space by

Weight Factors

(

)

G F L

λ

λ

−+ =

1

1/8

Problems with manual

weight adjustments:

goals and weight factors are

not inversely proportional

changing one

weight factor

affects all

other goals

Weight factors make the

solution space accessible, but are

target goal

F

ESTRO IMRT course 2016

IMRT optimization: algorithms&cost functions

London April 4th, 2016

-27-

normal tissue goal

G

7/8

5/8

6/8

4/8

3/8

2/8

not well suited for exploring it

during the search for the best

balance between goals.