Parametrisation of the Solution Space by
Weight Factors
(
)
G F L
λ
λ
−+ =
1
1/8
Problems with manual
weight adjustments:
goals and weight factors are
not inversely proportional
changing one
weight factor
affects all
other goals
Weight factors make the
solution space accessible, but are
target goal
F
ESTRO IMRT course 2016
IMRT optimization: algorithms&cost functions
London April 4th, 2016
-27-
normal tissue goal
G
7/8
5/8
6/8
4/8
3/8
2/8
not well suited for exploring it
during the search for the best
balance between goals.